EUFEST STUDY PDF

Either your web browser doesn't support Javascript or it is currently turned off. In the latter case, please turn on Javascript support in your web browser and reload this page. Free to read. Schizophrenia is a chronic disease most frequently necessitating lifelong antipsychotic treatment. Selecting which antipsychotic is to be prescribed in an individual schizophrenia patient represents an important clinical decision that need to take into account efficacy and side effects.

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Background: Predefined response and remission criteria may hold more clinical relevance than mean scores on rating scales. Analysis was by intention-to-treat. Comparisons with haloperidol showed a better chance for remission on amisulpride HR 2.

Conclusions: Substantial proportions of first-episode patients with schizophrenia showed clinically meaningful response and remission rates within 12 months. The proportions of response and remission were higher for most SGAs as compared to haloperidol.

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Kahn RS, et al. Volavka J, et al. J Clin Psychiatry. Pijnenborg GH, et al. Eur Neuropsychopharmacol. Epub Apr Using antipsychotic agents in older patients. Alexopoulos GS, et al. PMID: Review. Time to all-cause treatment discontinuation of olanzapine compared to other antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis. Soares-Weiser K, et al. Epub May Show more similar articles See all similar articles.

Cited by 30 articles Common increased hippocampal volume but specific changes in functional connectivity in schizophrenia patients in remission and non-remission following electroconvulsive therapy: A preliminary study. Jiang Y, et al. Neuroimage Clin. Epub Nov 8. Bozzatello P, et al. Front Psychiatry. Evaluation of SYA as a new potential antipsychotic agent without catalepsy. Bricker BA, et al. Pharmacol Biochem Behav. Epub Feb Continue, adjust, or stop antipsychotic medication: developing and user testing an encounter decision aid for people with first-episode and long-term psychosis.

Zisman-Ilani Y, et al. BMC Psychiatry. Zhang X, et al. Neurosci Bull. Show more "Cited by" articles See all "Cited by" articles. Publication types Multicenter Study Actions. Randomized Controlled Trial Actions. Research Support, Non-U. Gov't Actions. MeSH terms Adolescent Actions. Adult Actions. Cross-Cultural Comparison Actions. Dose-Response Relationship, Drug Actions.

Europe Actions. Female Actions. Humans Actions. International Cooperation Actions. Israel Actions. Male Actions. Outcome Assessment, Health Care Actions. Predictive Value of Tests Actions.

Proportional Hazards Models Actions. Psychiatric Status Rating Scales Actions. Retrospective Studies Actions. Secondary Prevention Actions. Time Factors Actions. Young Adult Actions. Substances Antipsychotic Agents Actions. Full-text links [x] Elsevier Science. Copy Download.

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The European First Episode Schizophrenia Trial (EUFEST): Rationale and Design of the Trial

Background: Predefined response and remission criteria may hold more clinical relevance than mean scores on rating scales. Analysis was by intention-to-treat. Comparisons with haloperidol showed a better chance for remission on amisulpride HR 2. Conclusions: Substantial proportions of first-episode patients with schizophrenia showed clinically meaningful response and remission rates within 12 months. The proportions of response and remission were higher for most SGAs as compared to haloperidol.

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WEIGHT GAIN AND ANTIPSYCHOTICS. DATA FROM EUFEST STUDY.

Background: Most studies comparing second generation antipsychotics with classical neuroleptics have been conducted in more or less chronic schizophrenia patients. Such studies were usually conducted in highly selected samples, and were generally designed and financed by the manufacturer of the drug tested. These and other facts have stimulated discussions regarding the effectiveness of the new generation of antipsychotics. Aims: The aim of the European First Episode Schizophrenia Trial EUFEST is to compare treatment with amisulpride, quetiapine, olanzapine and ziprasidone to a low dose of haloperidol in an unselected sample of first episode schizophrenia patients with minimal prior exposure to antipsychotics.

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